Is it possible to abandon the suffering of samsara and pass beyond the suffering of samsara? If the world were created by a god, then we would be helpless. It would not be within our power to do much about our own situation, and achieve real happiness. However, some deity has not created the world, so we have the power to do something about our situation. That is because the situation we are in is the fruition of our own actions; our actions are a cause that has created this particular effect. Therefore, it is within our power to abandon the causes of suffering.
For instance, we hear about the great suffering that beings have to undergo in the lower realms and we feel frightened by that and do not want to have to experience that kind of suffering. So, is it within our power to prevent the experience of this kind of suffering? Yes, it is because ill deeds and non-virtuous activities are the causes of being born in a lower realm. And it is within our power not to engage in such ill deeds. In that way, it is within our power to do what we want to do. If we want to achieve nirvana or the state of having crossed beyond all suffering of cyclic existence, we can simply engage in the causes that lead to nirvana.
From Pointing Out the Dharmakaya: Teachings on the Ninth Karmapa’s Text by Khenchen Thrangu Rinpoche, page 13.